List of 250cc/Moto2 World Riders' Champions

Grand Prix motorcycle racing is the premier championship of motorcycle road racing, which has been divided into three classes: MotoGP, Moto2, and Moto3. Former classes that have been discontinued include 350cc, 250cc, 125cc, 50cc/80cc, MotoE, and Sidecar. 250cc is the intermediate category; the 250cc refers to the size of the engines of the motorcycles that race in that class. For the engines configuration is inline-four since 2010 until 2018 and changed to inline-three since 2019. The Grand Prix Road-Racing World Championship was established in 1949 by the sport's governing body, the Fédération Internationale de Motocyclisme (FIM), and is the oldest motorsport world championship. The 250cc class was replaced in 2010 by a new class called Moto2. The 250cc engines were replaced by 600cc engines, which were supplied by Honda to all teams. Since 2019, the Moto2 class engines are supplied by Triumph to all teams, and changed the engines from 600cc to 765cc.

Points earned in these events count toward the riders' and constructors' world championships. The rider's and constructor's championship are separate championships, but are based on the same point system. The number of points awarded at the end of each race to the top 15 qualifying riders depends on their placement. Points received by each finisher, from first 1st place to 15th place: 25, 20, 16, 13, 11, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1. Historically, there have been several points systems. Results from all current Grands Prix count towards the championships; in the past, only a certain number of results were counted.

Phil Read and Max Biaggi have won the most championships, with four each. Dani Pedrosa is the youngest to win the championship; he was 19 years and 18 days old when he won the championship in 2004. Italian riders have won the most championships; 16 riders have won a total of 25 championships. Riders from Spain have won the second most; ten riders have won a total of thirteen championships. Great Britain have won the third most, as four riders have won a total of nine championships. Bruno Ruffo won the inaugural championship in 1949. Hiroshi Aoyama was the last rider to win the 250cc championship in 2009. Toni Elías was the first champion of the Moto2 category. Diogo Moreira is the current champion; he won the 2025 Moto2 World Championship.