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Zusanli

Acupuncture point below the knee

Zusanli
Summary

Acupuncture point below the knee

Zusanli (, ST36) is an acupoint, a point of the skin that is stimulated, with various techniques, in the practice of acupuncture. It is located below the knee, on the tibialis anterior muscle, along the stomach meridian.

A Japanese diagram explaining how to find the zusanli acupoint, which is located 4 fingers below the [[tibialis anterior muscle]]

Therapeutic uses and scientific validation

Acupuncture of Zusanli induces local serotonin release. Furthermore, the stimulation of this acupoint is shown to decrease inflammation, as evidenced by decreased cytokines (including interleukin 6) and inhibition of edema in a rat model of inflammation involving carrageenan injection.{{cite journal An analgesic effect, mediated in part by nitric oxide as well, through the upregulation of inducible nitric oxide synthase (iNOS),{{cite journal |doi-access=free

The stimulation of Zusanli decreases the locomotor activity elicited by nicotine administration and decreases Fos-like immunoreactivity in the basal ganglia (e.g., the striatum, particularly the nucleus accumbens) in a rat model of nicotine sensitisation. Those changes in the basal ganglia also improve the alcohol withdrawal syndrome in similar experimental conditions.{{cite journal

References

References

  1. (2017). "Acupuncture causes serotonin release by mast cells.". Romanian Journal of Morphology and Embryology.
  2. (2004). "Acupuncture attenuates repeated nicotine-induced behavioral sensitization and c-Fos expression in the nucleus accumbens and striatum of the rat". Neurosci. Lett..
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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