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Yaba monkey tumor virus

Species of virus

Field	Value
name	Yaba monkey tumor virus
image	Monkey (Bonnet macaque).jpg
field	Infectious disease

Yaba monkey tumor virus is a type of poxvirus. The first case of the virus was obtained from a colony of rhesus monkeys in Yaba, Lagos, Nigeria. The virus caused the formation of tumors on the bodies of the monkeys. From these tumors the virus was isolated and determined to be its own species of virus. It is a species of the Yatapoxvirus genus and is closely related to the tanapox. The virus gets its name from the suburb of Yaba, Lagos.

Signs and symptoms

Yaba monkey tumor virus is characterized by the formation of cutaneous histiocytomas. These cutaneous histiocytomas may form on the face, palms, digits, forearm, surfaces of the nose, sinuses, lips, and palate. In rhesus monkeys the virus has a tendency to affect the face and sinuses causing large tumors to form. In general the only symptoms of the virus will be the formation of tumors.

Virus

Yaba monkey tumor virus (YMTV) is considered a chordopoxvirus due to its ability to infect vertebrates and consists of linear double-stranded DNA. The vaccinia virus is a known prevention method for the Mpox virus through intradermal inoculation; however, it has been found that intradermal inoculation of the vaccinia virus does not provide resistance to the Yaba monkey tumor virus.

YMTV is similar to the closely related Tanapox virus.

Treatment

The tumors are known to resolve on their own after between 2–3 months after infection. Currently the best known treatment for the virus is the removal of the cutaneous tumors and subsequent treatment with antibiotics to prevent infection of the open wounds.

The best method of preventing infection is to wear gloves and protective clothing while handling infected primates.

Epidemiology and history

The virus was first visualized after an outbreak of cutaneous histiocytomas in rhesus monkeys which were kept outdoors in 1956 Yaba, Lagos, Nigeria. The virus has not been yet been observed in wild animals. This virus is transmittable to humans and has been transmitted in the past through handling of the monkeys, the symptoms are generally the same observed in the monkeys. There have only been a few cases of the virus transmitting to humans, with little documentation.

References

"Yaba monkey tumor virus".
(2008-01-01). "Yaba Monkey Tumor Virus Encodes a Functional Inhibitor of Interleukin-18". Journal of Virology.
(2008). "Infectious Diseases of Wild Mammals". Wiley.
(2003-12-15). "Complete Genomic Sequence and Comparative Analysis of the Tumorigenic Poxvirus Yaba Monkey Tumor Virus". Journal of Virology.
(1973). "Monkeypox Virus". Bacteriol Rev.
(May 1966). "The Fine Structure of the Yaba Monkey Tumor Poxvirus". Cancer Res.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

chordopoxvirinae yaba,-lagos

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