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Venturicidin

Group of chemical compounds

Group of chemical compounds

Venturicidins (also known as aabomycins) are a group of antifungal compounds. The first member of this class was isolated from Streptomyces bacteria in 1961. Additional members of this class were subsequently isolated and characterized. An antifungal substance "aabomycin A" was isolated from Streptomyces in 1969. However, in 1990 it was reported that aabomycin A is actually a 3:1 mixture of two related components, which were then named aabomycin A1 and aabomycin A2. The structures of these were shown to be identical with those of the previously characterized compounds venturicidin A and venturicidin B, respectively.

Venturicidins are active against Pyricularia oryzae and Trichophyton species.

Chemical structures

Aabomycin A1.svg|Venturicidin A (aabomycin A1) Aabomycin A2.svg|Venturicidin B (aabomycin A2)

References

References

  1. (1961). "Venturicidin: A new antifungal antibiotic of potential use in agriculture". Nature.
  2. (1968). "Metabolic products of microorganisms. LXIX. Venturicidin B, cotrycidin, and the sugar structural units of venturicidin A and B". Helvetica Chimica Acta.
  3. (1969). "Aabomycin A, a new antibiotic. I. Production, isolation, and properties of aabomycin A". Journal of Antibiotics.
  4. (1969). "Aabomycin A, a new antibiotic. II. Biological studies on aabomycin A". Journal of Antibiotics.
  5. (1990). "Identity of aabomycin A with venturicidins". Agricultural and Biological Chemistry.
  6. (March 2014). "Venturicidin C, a new 20-membered macrolide produced by ''Streptomyces'' sp. TS-2-2.". The Journal of Antibiotics.
  7. (1988). "Pesticide Chemistry". Elsevier.
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