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UDP-N-acetylgalactosamine diphosphorylase

Class of enzymes

Summary

Class of enzymes

Field	Value
Name	UDP-N-acetylgalactosamine diphosphorylase
EC_number	2.7.7.83

UDP-N-acetylgalactosamine diphosphorylase () is an enzyme with systematic name UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase. This enzyme catalyses the following chemical reaction

: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate \rightleftharpoons diphosphate + UDP-N-acetyl-alpha-D-galactosamine

The enzyme from plants and animals also acts on N-acetyl-alpha-D-glucosamine 1-phosphate.

References

(October 1998). "A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc". The Journal of Biological Chemistry.
(November 2001). "Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture". The EMBO Journal.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-2.7.7

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