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Tropine acyltransferase
| Field | Value |
|---|---|
| Name | Tropine acyltransferase |
| EC_number | 2.3.1.185 |
| CAS_number | 138440-79-6, 162535-29-7 |
Tropine acyltransferase (, tropine:acyl-CoA transferase, acetyl-CoA:tropan-3-ol acyltransferase, tropine acetyltransferase, tropine tigloyltransferase, TAT) is an enzyme with systematic name acyl-CoA:tropine O-acyltransferase. This enzyme catalyses the following chemical reaction
: acyl-CoA + tropine \rightleftharpoons CoA + O-acyltropine
This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine.
References
References
- (November 1991). "The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases". FEBS Letters.
- (1994). "Esterification reactions in the biosynthesis of tropane alkaloids in transformed root cultures". Plant Cell Tissue Organ Cult..
- (November 1999). "Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura". Phytochemistry.
- (May 2006). "Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement". Chemistry & Biology.
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