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TRNAMet cytidine acetyltransferase


FieldValue
NameTRNAMet cytidine acetyltransferase
EC_number2.3.1.193

TRNAMet cytidine acetyltransferase (, YpfI, TmcA) is an enzyme with systematic name acetyl-CoA:(elongator tRNAMet)-cytidine34 N4-acetyltransferase (ATP-hydrolysing). This enzyme catalyses the following chemical reaction

: [elongator tRNAMet]-cytidine34 + ATP + acetyl-CoA \rightleftharpoons CoA + [elongator tRNAMet]-N4-acetylcytidine34 + ADP + phosphate

The enzyme acetylates the wobble base C34 of the CAU anticodon of elongation-specific tRNAMet.

References

References

  1. (August 2008). "The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon". The EMBO Journal.
  2. (May 2009). "RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon". The EMBO Journal.
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