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TRNAMet cytidine acetyltransferase
| Field | Value |
|---|---|
| Name | TRNAMet cytidine acetyltransferase |
| EC_number | 2.3.1.193 |
TRNAMet cytidine acetyltransferase (, YpfI, TmcA) is an enzyme with systematic name acetyl-CoA:(elongator tRNAMet)-cytidine34 N4-acetyltransferase (ATP-hydrolysing). This enzyme catalyses the following chemical reaction
: [elongator tRNAMet]-cytidine34 + ATP + acetyl-CoA \rightleftharpoons CoA + [elongator tRNAMet]-N4-acetylcytidine34 + ADP + phosphate
The enzyme acetylates the wobble base C34 of the CAU anticodon of elongation-specific tRNAMet.
References
References
- (August 2008). "The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon". The EMBO Journal.
- (May 2009). "RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon". The EMBO Journal.
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