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TRNA (guanine6-N2)-methyltransferase


FieldValue
NameTRNA (guanine6-N2)-methyltransferase
EC_number2.1.1.256

TRNA (guanine6-N2)-methyltransferase (, methyltransferase Trm14, m2G6 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + guanine6 in tRNA \rightleftharpoons S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA

The enzyme specifically methylates guanine6 at N2 in tRNA.

References

References

  1. (September 2011). "Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14". Nucleic Acids Research.
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