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TRNA (guanine26-N2/guanine27-N2)-dimethyltransferase

Enzyme

Summary

Enzyme

Field	Value
Name	TRNA (guanine26-N2/guanine27-N2)-dimethyltransferase
EC_number	2.1.1.215

TRNA (guanine26-N2/guanine27-N2)-dimethyltransferase (, Trm1, tRNA (N2,N2-guanine)-dimethyltransferase, tRNA (m2(2G26) methyltransferase, Trm1[tRNA (m2(2)G26) methyltransferase]) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase. This enzyme catalyses the following chemical reaction

: 4 S-adenosyl-L-methionine + guanine26/guanine27 in tRNA \rightleftharpoons 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26/N2-dimethylguanine27 in tRNA

The enzyme from Aquifex aeolicus is similar to the TRM1 methyltransferases of archaea and eukarya.

References

(July 2009). "Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA". The Journal of Biological Chemistry.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-2.1.1

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