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TRNA-guanine15 transglycosylase

Class of enzymes

Field	Value
Name	TRNA-guanine15 transglycosylase
EC_number	2.4.2.48

TRNA-guanine15 transglycosylase (, tRNA transglycosylase, transfer ribonucleate glycosyltransferase, tRNA guanine15 transglycosidase, TGT, transfer ribonucleic acid guanine15 transglycosylase) is an enzyme with systematic name tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase. This enzyme catalyses the following chemical reaction

: guanine15 in tRNA + 7-cyano-7-carbaguanine \rightleftharpoons 7-cyano-7-carbaguanine15 in tRNA + guanine

Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.

References

(September 2000). "Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii". The Journal of Biological Chemistry.

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ec-2.4.2

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