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TRNA (adenine58-N1)-methyltransferase

Field	Value
Name	TRNA (adenine58-N1)-methyltransferase
EC_number	2.1.1.220

TRNA (adenine58-N1)-methyltransferase (, tRNA m1A58 methyltransferase, tRNA (m1A58) methyltransferase, TrmI, tRNA (m1A58) Mtase, Rv2118cp, Gcd10p-Gcd14p, Trm61p-Trm6p) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine58-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + adenine58 in tRNA \rightleftharpoons S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA

The enzyme specifically methylates adenine58 in tRNA.

References

(April 2003). "Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures". Nucleic Acids Research.
(2004). "Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase". Nucleic Acids Research.
(May 2000). "The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae". Proceedings of the National Academy of Sciences of the United States of America.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-2.1.1

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