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TRNA (adenine22-N1)-methyltransferase

Field	Value
Name	TRNA (adenine22-N1)-methyltransferase
EC_number	2.1.1.217

TRNA (adenine22-N1)-methyltransferase (, TrmK, YqfN, Sp1610 (gene), tRNA: m1A22 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine22-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + adenine22 in tRNA \rightleftharpoons S-adenosyl-L-homocysteine + N1-methyladenine22 in tRNA

The enzyme specifically methylates adenine22 in tRNA.

References

(March 2010). "Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine". Protein Science.
(June 2008). "The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK)". Nucleic Acids Research.

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ec-2.1.1

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