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Tricetin 3',4',5'-O-trimethyltransferase

Class of enzymes

Summary

Class of enzymes

FieldValue
NameTricetin 3',4',5'-O-trimethyltransferase
EC_number2.1.1.169

Tricetin 3',4',5'-O-trimethyltransferase (, FOMT, TaOMT1, TaCOMT1, TaOMT2) is an enzyme with systematic name S-adenosyl-L-methionine:tricetin 3',4',5'-O-trimethyltransferase. This enzyme catalyses the following chemical reaction

: 3 S-adenosyl-L-methionine + tricetin \rightleftharpoons 3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin (overall reaction) :(1a) S-adenosyl-L-methionine + tricetin \rightleftharpoons S-adenosyl-L-homocysteine + 3'-O-methyltricetin :(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin \rightleftharpoons S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin :(1c) S-adenosyl-L-methionine + 3',5'-O-dimethyltricetin \rightleftharpoons S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin

The enzyme from Triticum aestivum catalyses the sequential O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin.

References

References

  1. (May 2008). "Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience". The FEBS Journal.
  2. (July 2006). "Sequential O-methylation of tricetin by a single gene product in wheat". Biochimica et Biophysica Acta (BBA) - General Subjects.
  3. (April 2009). "Biochemical characterization of a putative wheat caffeic acid O-methyltransferase". Plant Physiology and Biochemistry.
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ec-2.1.1 o-methylated-flavones-metabolism
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