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Treatment of warts by keratolysis

Therapy for warts

Treatment of warts by keratolysis
Summary

Therapy for warts

date=July 2019}}

Formulations

Some formulations are:

  • alcoholic solution containing glycerol
  • collodion which dries to a celluloid film / Duofilm
  • simple ointment
  • absorption ointment
  • oil in water cream

The amount of salicylic acid reaching the wart varies substantially depending on the formulation used. Brands in the UK include Bazuka (Dendron), Scholl (SSL International), Compound W, Cuplex gel, Duofilm (Stiefel), Occlusal (Alliance), Salatac Gel, Salactol Paint, and Verrugon (Ransom).

Molecular basis of therapeutic effect

  • Salicylic acid reaches warts; lactic acid and collodion do not. Therefore, these additional components have only an indirect role in therapy.
  • The molecular structure of the skin is altered at the centre of the wart.
  • Experiments indicated that salicylic acid bonding within the human papillomavirus-containing verruca tissue is more likely than simple acid dissociation upon dissolution in water within the tissue.

Complications

Some cases of allergic contact dermatitis have been observed when using collodion formulations. This was found to be due to rosin in the collodion.

References

References

  1. "Bazuka extra strength gel". Netdoctor.
  2. Nathan, Alan. (2010-06-17). "Non-Prescription Medicines". Pharmaceutical Press.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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