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Tetrahydroharmol

Chemical compound

Field	Value
drug_name	Tetrahydroharmol
image	Tetrahydroharmol.svg
image_class	skin-invert-image
width	225px
image2	Tetrahydroharmol 3D.png
image_class2	bg-transparent
width2	200px
CAS_number	17952-75-9
UNII_Ref
UNII	DHR7GV467K
PubChem	368982
ChemSpiderID	327573
ChEMBL	14122
synonyms	1,2-Dihydroharmaline
IUPAC_name	1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-7-ol
C	12	H=14	N=2	O=1
SMILES	CC1C2=C(CCN1)C3=C(N2)C=C(C=C3)O
StdInChI	1S/C12H14N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-3,6-7,13-15H,4-5H2,1H3
StdInChIKey	AZTMWIPCEFFOJD-UHFFFAOYSA-N

| Drugs.com =

| elimination_half-life =

Tetrahydroharmol is a bioactive β-carboline and harmala alkaloid. It acts as a reversible inhibitor of monoamine oxidase A.

Society and culture

Legal status

Australia

Harmala alkaloids are considered Schedule 9 prohibited substances under the Poisons Standard (October 2015). A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.

References

(2012). "Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca". Drug Testing and Analysis.
(November 1977). "Monoamine oxidase inhibition in brain and liver produced by beta-carbolines: structure-activity relationships and substrate specificity". Elsevier BV.
(September 2015). "Poisons Standard October 2015". Australian Government Department of Health.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

beta-carbolines n-monoalkyltryptamines monoamine-oxidase-inhibitors tryptamine-alkaloids

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