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general/ec-1-14-13

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Taxoid 14beta-hydroxylase


FieldValue
NameTaxoid 14beta-hydroxylase
EC_number1.14.13.146

Taxoid 14beta-hydroxylase () is an enzyme with systematic name 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl-acetate,NADPH:oxygen 14-oxidoreductase. This enzyme catalyses the following chemical reaction

: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ \rightleftharpoons 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O

Taxoid 14beta-hydroxylase requires cytochrome P450.

References

References

  1. (May 2003). "Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase". Archives of Biochemistry and Biophysics.
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