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Succinylation

Addition of a succinyl group to a lysine group of a protein


Addition of a succinyl group to a lysine group of a protein

In biochemistry, succinylation is a posttranslational modification where a succinyl group () is added to a lysine residue of a protein molecule. This modification is found in many proteins, including histones.{{Cite journal | doi-access = free

By analogy to acetylation, it has been suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine succinylation.

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