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Staphylococcus aureus beta toxin

Toxin produced by Staphylococcus aureus

Summary

Toxin produced by Staphylococcus aureus

Staphylococcus aureus beta toxin is a toxin produced by Staphylococcus aureus. It is a form of sphingomyelinase called sphingomyelinase C. This enzyme is toxic to a variety of cells, including erythrocytes, fibroblasts, leukocytes, and macrophages. Susceptible cells are subject to lysis of exposed sphingomyelin on their membrane surfaces.

The beta toxin exhibits maximum activity at 10 °C, at 37 °C (normal body temperature) seems to be inactive.

References

(February 1996). "Effect of staphylococcal β toxin on the cytotoxicity, proliferation and adherence of ''Staphylococcus aureus'' to bovine mammary epithelial cells". Veterinary Microbiology.
(February 1997). "Purification of ''Staphylococcus aureus'' β-toxin: comparison of three isoelectric focusing methods". Protein Expression and Purification.
(2009). "Medical Microbiology". Mosby.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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