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Squamous cell papilloma

FieldValue
nameSquamous cell papilloma
synonymsSquamous papilloma
imageSquamous papilloma -- very low mag.jpg
captionMicrograph showing a squamous papilloma of the tongue. H&E stain.

A squamous cell papilloma is a generally benign papilloma that arises from the stratified squamous epithelium of the skin, lip, oral cavity, tongue, pharynx, larynx, esophagus, cervix, vagina or anal canal. Squamous cell papillomas are typically associated with human papillomavirus (HPV) while sometimes the cause is unknown.

Types

Oral squamous cell papilloma

Squamous cell papilloma of the mouth or throat is generally diagnosed in people between the ages of 30 and 50, and is normally found on the inside of the cheek, on the tongue, or inside of lips. Oral papillomas are usually painless and not treated unless they interfere with eating or cause pain. They do not generally mutate to cancerous growths, nor do they normally grow or spread. Oral papillomas are usually a result of the infection with types HPV-6 and HPV-11.

Conjunctival squamous cell papilloma

Normally found in children or young adults, a common cause of conjunctival squamous cell papilloma is during childbirth, when the mother passes the virus to her child.

Diagnosis

It appears as an exophytic mass with a cauliflower-like appearance. The lesion may be white, red, or normal in color. It appears as a sessile or pedunculated mass. Histopathology typically shows papillomatosis protrusions and/or dysplasia. File:Gross pathology of a large squamous cell papilloma.jpg|Gross pathology of a large squamous cell papilloma File:Histopathology of a large squamous cell papilloma.jpg|Histopathology of the same papilloma.

Treatment

While most cases require no treatment, therapy options include cryotherapy, application of a topical salicylic acid compound, surgical excision and laser ablation.

References

References

  1. New Zealand Dermatological Society. (2007). "Squamous cell papilloma". New Zealand Dermatological Society.
  2. Nikon Microscopy. (2007). "Squamous Cell Papilloma". Nikon Microscopy.
  3. National Library for Health. (2007). "Squamous cell papilloma". National Library for Health.
  4. Stojanov, Ivan J.. (2013). "Squamous cell papilloma". PathologyOutlines.com.
  5. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. (2014). "Association of human papilloma virus with atypical and malignant oral papillary lesions". Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.
  6. American Cancer Society. (2000). "Squamous papilloma of the urinary tract". Cancer.
  7. Elsevier Inc.. (1994). "Squamous cell papillomas of the esophagus". Human Pathology.
  8. {{EMedicine. oph. 611. Papilloma, Conjunctival
  9. Nat Pernick. "Oral cavity - Other benign tumors / conditions - Squamous papilloma".
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

benign-neoplasms papillomavirus-associated-diseases
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