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Site-specific DNA-methyltransferase (cytosine-N4-specific)

Class of enzymes

Class of enzymes

FieldValue
NameSite-specific DNA-methyltransferase (cytosine-N4-specific)
EC_number2.1.1.113
CAS_number169592-50-1

Site-specific DNA-methyltransferase (cytosine-N4-specific) (, modification methylase, restriction-modification system, DNA[cytosine-N4]methyltransferase, m4C-forming MTase, S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase. This enzyme catalyses the following chemical reaction:

: S-adenosyl-L-methionine + DNA cytosine \rightleftharpoons S-adenosyl-L-homocysteine + DNA N4-methylcytosine

This is a large group of enzymes.

References

References

  1. (August 1990). "Specificity of restriction endonucleases and DNA modification methyltransferases a review (Edition 3)". Gene.
  2. (December 1989). "Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases". Nucleic Acids Research.
  3. (April 1990). "Restriction enzymes and their isoschizomers". Nucleic Acids Research.
  4. (1981). "Structure and mechanism of multifunctional restriction endonucleases". Annual Review of Biochemistry.
  5. "A complete listing of all of these enzymes". The Restriction Enzyme Database.
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