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Secnidazole

Chemical compound

Chemical compound

| Drugs.com =

| elimination_half-life =

Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a nitroimidazole anti-infective used to treat bacterial vaginosis and trichomoniasis. It is taken orally.

Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae.

In the United States, secnidazole is FDA-approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. It was approved in the United States in 2017.

References

References

  1. (24 February 2025). "Evofem Biosciences".
  2. [https://web.archive.org/web/20220225002852/https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/209363Orig1s014s016lbl.pdf fda.gov]
  3. (February 2003). "Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole". Clinical Microbiology and Infection.
  4. (May 2010). "In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis". Clinical Microbiology and Infection.
  5. (April 2022). "Secnidazole for Trichomoniasis in Women and Men". Sex Med Rev.
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