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general/post-translational-modification

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S-Glutathionylation


S-Glutathionylation is the posttranslational modification of protein cysteine residues by the addition of glutathione, the most abundant and important low-molecular-mass thiol within most cell types.{{cite journal

Protein S-glutathionylation is involved in

  • oxidative stress
  • nitrosative stress
  • preventing irreversible oxidation of protein thiols
  • control of cell-signalling pathways by modulating protein function

References

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