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Rectoanal inhibitory reflex
Body reflex
Body reflex
The rectoanal inhibitory reflex (RAIR), also known as the anal sampling mechanism, anal sampling reflex, rectosphincteric reflex, or anorectal sampling reflex, is a reflex characterized by a transient involuntary relaxation of the internal anal sphincter in response to distention of the rectum. The RAIR provides the upper anal canal with the ability to discriminate between flatus and fecal material.
The ability of the rectum to discriminate between gaseous, liquid and solid contents is essential to the ability to voluntarily control defecation. The RAIR allows for voluntary flatulation to occur without also eliminating solid waste, irrespective of the presence of fecal material in the anal canal.
Reflex arc
The physiological basis for the RAIR is poorly understood, but it is thought to involve a coordinated response by the internal anal sphincter to rectal distention with recovery of anal pressure from the distal to the proximal sphincter.
Clinical significance
Impairment of this reflex can result in fecal incontinence. The absence of a RAIR is pathognomonic for Hirschsprung's disease.
References
References
- (February 1998). "Parameters of the rectoanal inhibitory reflex in patients with idiopathic fecal incontinence and chronic constipation". Diseases of the Colon and Rectum.
- (2014). "Gastrointestinal Physiology". Lange Medical Books/McGraw-Hill.
- (January 2004). "Pathophysiology of adult fecal incontinence". Gastroenterology.
- (August 2005). "Interstitial cells of Cajal are involved in the afferent limb of the rectoanal inhibitory reflex". Gut.
- (2005). "Complex Anorectal Disorders: Investigation and Management". Springer Science+Business Media.
- (November 1998). "The recto-anal inhibitory reflex: abnormal response in diabetics suggests an intrinsic neuroenteropathy". Journal of Gastroenterology and Hepatology.
- (June 2008). "Neurophysiological testing in anorectal disorders". Expert Review of Gastroenterology & Hepatology.
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