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Pseudotropine acyltransferase

Enzyme


Summary

Enzyme

FieldValue
NamePseudotropine acyltransferase
EC_number2.3.1.186
CAS_number138440-78-5, 162535-26-4

Pseudotropine acyltransferase (, pseudotropine:acyl-CoA transferase, tigloyl-CoA:pseudotropine acyltransferase, acetyl-CoA:pseudotropine acyltransferase, pseudotropine acetyltransferase, pseudotropine tigloyltransferase, PAT) is an enzyme with systematic name acyl-CoA:pseudotropine O-acyltransferase. This enzyme catalyses the following chemical reaction

: acyl-CoA + pseudotropine \rightleftharpoons CoA + O-acylpseudotropine

This enzyme exhibits absolute specificity for the exo/3beta configuration found in pseudotropine as tropine (tropan-3alpha-ol).

References

References

  1. (1995). "Tigloyl-CoA:pseudotropine acyltransferase — an enzyme of tropane alkaloid biosynthesis". Phytochemistry.
  2. (November 1991). "The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases". FEBS Letters.
  3. (1994). "Esterification reactions in the biosynthesis of tropane alkaloids in transformed root cultures". Plant Cell Tissue Organ Cult..
  4. (November 1999). "Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura". Phytochemistry.
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