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Protein-fructosamine 3-kinase
| Field | Value |
|---|---|
| Name | Protein-fructosamine 3-kinase |
| EC_number | 2.7.1.171 |
Protein-fructosamine 3-kinase (, FN3K, fructosamine 3-kinase) is an enzyme with systematic name ATP:(protein)-N6-D-fructosyl-L-lysine 3-phosphotransferase. This enzyme catalyses the following chemical reaction
: ATP + [protein]-N6-D-fructosyl-L-lysine \rightleftharpoons ADP + [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine
Nonenzymatic glycation is a factor in the pathogenesis of diabetes.
References
References
- (September 2001). "Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo". Diabetes.
- (October 2000). "Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase". Diabetes.
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