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Prostamide/prostaglandin F2alpha synthase

Field	Value
Name	Prostamide/prostaglandin F2alpha synthase
EC_number	1.11.1.20

Prostamide/prostaglandin F2alpha synthase (, prostamide/PGF synthase, prostamide F synthase, prostamide/prostaglandin F synthase, tPGF synthase) is an enzyme with systematic name *thioredoxin:(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate oxidoreductase *. This enzyme catalyses the following chemical reaction

: thioredoxin + (5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate \rightleftharpoons thioredoxin disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dienoate

This enzyme contains a thioredoxin-type disulfide as a catalytic group.

References

(January 2008). "Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily". The Journal of Biological Chemistry.
(January 2011). "Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system". Brain Research.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-1.11.1

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