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Proliferating trichilemmal cyst

Field	Value
name	Proliferating trichilemmal cyst
synonyms	Pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor
image	SkinTumors-P8240657.JPG
caption	Proliferating tricholemmal (pilar) cyst
field	Dermatology

Proliferating trichilemmal cysts (also known as a pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor) is a cutaneous condition, characterized by proliferations of squamous cells forming scroll-like structures.

Signs and symptoms

The tumors, which are typically found in regions like the scalp with a high density of hair follicles, can be solid or solid cystic. Proliferating trichilemmal cyst frequently manifests clinically as a subcutaneous nodule that gradually grows into a big nodular mass. Rapid growth in some cases may be a sign of malignant development into cancer.

Diagnosis

Histologically, Proliferating trichilemmal cysts are distinguished by trichilemmal keratinization, which is the sudden change from nucleated epithelium to anucleated keratinized cells without a granular layer. The differential diagnosis include trichilemmal cyst and Turban tumor.

Treatment

Surgical excision is the treatment of choice for proliferating trichilemmal cysts.

Epidemiology

Proliferating trichilemmal cysts make up 0.1% of all skin tumors. Most patients with these tumors are older women, and 90% of patients with these lesions appear on the scalp.

References

Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
James, William D.. (2006). "Andrews' Diseases of the Skin: Clinical Dermatology". Saunders Elsevier.
(2019). "Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation". FapUNIFESP (SciELO).
(2006-03-01). "Proliferating Trichilemmal Cysts of the Scalp on CT". American Journal of Neuroradiology.
(2016). "Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature". Hindawi Limited.
(2014). "Malignant proliferating trichilemmal tumor: A case report and review of literature". Journal of Cancer Research and Therapeutics.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

epidermal-nevi,-neoplasms,-and-cysts

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