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Placental site nodule

Human disease

Summary

Human disease

Field	Value
name	Placental site nodule
image	Placental site nodule - intermed mag.jpg
caption	Micrograph of a placental site nodule (top of image). H&E stain.

A placental site nodule (PSN) is benign remnant from a previous pregnancy.

Presentation

They are typically asymptomatic and found incidentally.

Pathology

PSNs are intermediate trophoblastic remnants.

Diagnosis

PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.

Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site.

Prognosis

PSN are benign. Once removed, they do not require any treatment and do not recur.

References

(2009). "Placental site nodule: a tumor-like trophoblastic lesion.". Indian J Pathol Microbiol.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

health-issues-in-pregnancy

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