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Pituitary disease
| Field | Value |
|---|---|
| name | Pituitary disease |
| image | Hypophyse.png |
| caption | Pituitary |
A pituitary disease is a disorder primarily affecting the pituitary gland. TOC
Table
The main disorders involving the pituitary gland are:
| Condition | Direction | Hormone |
|---|---|---|
| Acromegaly | overproduction | growth hormone |
| Gigantism | overproduction | growth hormone |
| Cushing's disease | overproduction | adrenocorticotropic hormone |
| Growth hormone deficiency | underproduction | growth hormone |
| Syndrome of inappropriate antidiuretic hormone | overproduction | vasopressin |
| Diabetes insipidus | ||
| (can also be nephrogenic) | underproduction | vasopressin |
| Sheehan syndrome | underproduction | any pituitary hormone |
| Pickardt-Fahlbusch Syndrome | underproduction | any pituitary hormone, except prolactin, which is increased |
| Hyperpituitarism (most commonly pituitary adenoma) | overproduction | any pituitary hormone |
| Hypopituitarism | underproduction | any pituitary hormone |
Overproduction or underproduction of a pituitary hormone will affect the respective end-organ. For example, insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.
References
References
- "Overview of the Pituitary Gland: Pituitary Gland Disorders: Merck Manual Home Health Handbook".
- Aminoff, Michael J.. (2007). "Neurology and General Medicine: Expert Consult: Online and Print". Churchill Livingstone.
- [http://www.uptodate.com/contents/thyrotropin-tsh-secreting-pituitary-adenomas Thyrotropin (TSH)-secreting pituitary adenomas.] By Roy E Weiss and Samuel Refetoff. Last literature review version 19.1: January 2011. This topic last updated: July 2, 2009
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