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Phosphoenolpyruvate carboxykinase (diphosphate)

Enzyme


Summary

Enzyme

FieldValue
NamePhosphoenolpyruvate carboxykinase (diphosphate)
EC_number4.1.1.38
CAS_number2598306
image6k31.jpg
width270
captionPhosphoenolpyruvate carboxykinase (pyrophosphate) homodimer, Actinomyces israelii
namePhosphoenolpyruvate carboxykinase (diphosphate)

Phosphoenolpyruvate carboxykinase (diphosphate) () is an enzyme with systematic name diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming). This enzyme catalyses the following chemical reaction

: diphosphate + oxaloacetate \rightleftharpoons phosphate + phosphoenolpyruvate + CO2

This enzyme also catalyses the reaction: :phosphoenolpyruvate + GTP + CO2 \rightleftharpoons pyruvate + GDP.

It is transcriptionally upregulated in the liver by glucagon.

References

References

  1. (December 1966). "Phosphoenolpyruvate carboxytransphosphorylase. II. Crystallization and properties". The Journal of Biological Chemistry.
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