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Phosphoenolpyruvate carboxykinase (diphosphate)
Enzyme
Enzyme
| Field | Value |
|---|---|
| Name | Phosphoenolpyruvate carboxykinase (diphosphate) |
| EC_number | 4.1.1.38 |
| CAS_number | 2598306 |
| image | 6k31.jpg |
| width | 270 |
| caption | Phosphoenolpyruvate carboxykinase (pyrophosphate) homodimer, Actinomyces israelii |
| name | Phosphoenolpyruvate carboxykinase (diphosphate) |
Phosphoenolpyruvate carboxykinase (diphosphate) () is an enzyme with systematic name diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming). This enzyme catalyses the following chemical reaction
: diphosphate + oxaloacetate \rightleftharpoons phosphate + phosphoenolpyruvate + CO2
This enzyme also catalyses the reaction: :phosphoenolpyruvate + GTP + CO2 \rightleftharpoons pyruvate + GDP.
It is transcriptionally upregulated in the liver by glucagon.
References
References
- (December 1966). "Phosphoenolpyruvate carboxytransphosphorylase. II. Crystallization and properties". The Journal of Biological Chemistry.
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