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Phorate

3911 (trademark)

Phorate is an organophosphate used as an insecticide and acaricide.

Overview

At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including humans. It inhibits acetylcholinesterase and butyrylcholinesterase.

Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.

Toxicity

Phorate (Thimate) is absorbed readily through all ways. Its toxicity is high. Oral LD50 to rats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.

References

References

  1. Farm Chemicals Handbook, Meister Publishing Co., Willoughby, OH (1991)
  2. {{PGCH. 0502
  3. "Data sheets on pesticides No. 75 – Phorate".
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

acetylcholinesterase-inhibitors organophosphate-insecticides organosulfur-compounds ethyl-esters
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