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Phenylacetyl-CoA 1,2-epoxidase

Class of enzymes


Summary

Class of enzymes

FieldValue
NamePhenylacetyl-CoA 1,2-epoxidase
EC_number1.14.13.149

Phenylacetyl-CoA 1,2-epoxidase (, ring 1,2-phenylacetyl-CoA epoxidase, phenylacetyl-CoA monooxygenase, PaaAC, PaaABC(D)E) is an enzyme with systematic name phenylacetyl-CoA:oxygen oxidoreductase (1,2-epoxidizing). This enzyme catalyses the following chemical reaction

: phenylacetyl-CoA + NADPH + H+ + O2 \rightleftharpoons 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O

Phenylacetyl-CoA 1,2-epoxidase participates in catabolism of phenylacetate in Escherichia coli and Pseudomonas putida.

References

References

  1. (August 2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proceedings of the National Academy of Sciences of the United States of America.
  2. (September 2010). "Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of the Escherichia coli phenylacetyl-coenzyme A oxygenase complex". Acta Crystallographica Section F.
  3. (March 2011). "Structural and functional studies of the Escherichia coli phenylacetyl-CoA monooxygenase complex". The Journal of Biological Chemistry.
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