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Phenylacetyl-CoA 1,2-epoxidase
Class of enzymes
Class of enzymes
| Field | Value |
|---|---|
| Name | Phenylacetyl-CoA 1,2-epoxidase |
| EC_number | 1.14.13.149 |
Phenylacetyl-CoA 1,2-epoxidase (, ring 1,2-phenylacetyl-CoA epoxidase, phenylacetyl-CoA monooxygenase, PaaAC, PaaABC(D)E) is an enzyme with systematic name phenylacetyl-CoA:oxygen oxidoreductase (1,2-epoxidizing). This enzyme catalyses the following chemical reaction
: phenylacetyl-CoA + NADPH + H+ + O2 \rightleftharpoons 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O
Phenylacetyl-CoA 1,2-epoxidase participates in catabolism of phenylacetate in Escherichia coli and Pseudomonas putida.
References
References
- (August 2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proceedings of the National Academy of Sciences of the United States of America.
- (September 2010). "Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of the Escherichia coli phenylacetyl-coenzyme A oxygenase complex". Acta Crystallographica Section F.
- (March 2011). "Structural and functional studies of the Escherichia coli phenylacetyl-CoA monooxygenase complex". The Journal of Biological Chemistry.
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