Peripheral odontogenic fibroma

Signs and symptoms

Peripheral odontogenic fibroma manifests clinically as an infrequent, benign, unencapsulated exophytic mass that can be sessile or pedunculated, red or pink, smooth-surfaced, and ulcerated in some cases. It is frequently found on the attached gingiva, mainly in the molar and premolar regions, though it can be found anywhere in the jaw.

Diagnosis

Clinically, there is no way to differentiate peripheral odontogenic fibroma from other common fibrous gingival lesions, including peripheral giant cell lesion, pyogenic granuloma, inflammatory fibrous hyperplasia, and peripheral ossifying fibroma. Rarely have diffuse or multifocal lesions been reported. Lesions that are larger may show signs of mineralization, although radiographic changes are uncommon, particularly in the early stages. Histopathologic features include a proliferation of relatively cellular fibrous or fibromyxomatous connective tissue with variable amounts of odontogenic epithelium and occasionally foci of calcification in the form of dentinoid, cementicles, or bone. These features are similar to those of the central odontogenic fibroma.

Treatment

The preferred course of treatment is conservative local excision.

Outlook

The rate of recurrence varies wildly. According to some studies, peripheral odontogenic fibroma has a low recurrence rate. One study showed a recurrence rate of 38.9%, while another study showed a recurrence rate of 50%.

Epidemiology

The literature has reported a slight female predominance in this neoplasm, which occurs in a wide age range from the first to the ninth decades of life with a peak in the second and fourth decades.

References

References

1. (2006). "Peripheral odontogenic fibroma (WHO type) of the newborn: a case report". Wiley.
2. (1992). "Histological Typing of Odontogenic Tumours". Springer Berlin Heidelberg.
3. (2015). "Peripheral odontogenic fibroma: A case report and review of literature". Medknow.
4. (2011). "Peripheral odontogenic fibroma: A case report and review". Medknow.
5. (2011). "Recurrent peripheral odontogenic fibroma. Case report". The New York State Dental Journal.
6. Gardner, David G.. (1982). "The peripheral odontogenic fibroma: An attempt at clarification". Elsevier BV.
7. Eversole, Lewis R.. (July 13, 2011). "Odontogenic Fibroma, Including Amyloid and Ossifying Variants". Springer Science and Business Media LLC.
8. (1991). "Peripheral odontogenic fibroma: A clinicopathologic study". Elsevier BV.
9. (1994). "Peripheral odontogenic fibroma". Elsevier BV.
10. (2010). "Peripheral odontogenic fibroma: a clinicopathologic study of 151 cases and review of the literature with special emphasis on recurrence". Elsevier BV.
11. (March 2007). "Retrospective analysis of peripheral odontogenic fibroma (WHO-type) in Brazilians". Minerva Stomatologica.