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Pancreatic serous cystadenoma

Field	Value
name	Pancreatic serous cystadenoma
synonyms	Serous cystadenoma of the pancreas, serous microcystic adenoma
image	Pancreatic serous cystadenoma - intermed mag.jpg
caption	Micrograph showing a pancreatic serous cystadenoma. H&E stain.
field	General surgery, gastroenterology
symptoms	Usually asymptomatic
onset	50–60 years of age
risks	Female gender
treatment	Surgical resection (if symptomatic)
deaths	0.1%

Pancreatic serous cystadenoma is a benign tumour of the pancreas. It is usually solitary and found in the body or tail of the pancreas, and may be associated with von Hippel–Lindau syndrome.

In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and the pancreatic mucinous cystadenoma), serous cystic neoplasms are almost always entirely benign. There are some exceptions; rare case reports have described isolated malignant serous cystadenocarcinomas. In addition, serous cystic neoplasms slowly grow, and if they grow large enough they can press on adjacent organs and cause symptoms.

Signs and symptoms

In most cases, serous cystadenomas of the pancreas are asymptomatic. However, large cysts may cause symptoms related to their size.

Classification

Pathologists classify serous cystic neoplasms into two broad groups. Those that are benign, that have not spread to other organs, are designated "serous cystadenoma". Serous cystadenomas can be further sub-typed into microcystic, oligocystic (or macrocystic), solid, mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because it highlights the range of appearances and the clinical associations of these neoplasms. Serous cystic neoplasms that have spread ("metastasized") to another organ are considered malignant and are designated "serous cystadenocarcinoma".

Pathology

File:Serous cystadenoma of the pancreatic head..jpg File:Pancreatic serous cystadenoma - intermed mag.jpg File:Pancreatic serous cystadenoma - high mag.jpg File:Pancreatic serous cystadenoma - very high mag.jpg File:Pancreatic serous cystadenoma (1).jpg File:Pancreatic serous cystic tumor (3).jpg

Treatment

These lesions rarely require surgery unless they are symptomatic or the diagnosis is in question. Since these lesions do not have malignant potential, long-term observation with imaging surveillance is unnecessary. In selected cases the surgery can be performed using minimally invasive techniques such as laparoscopy.

Epidemiology

pmc= }}<br>Diagram by Mikael Häggström, M.D.</ref>

Serous cystadenomas of the pancreas are more common in women.

References

(February 2016). "Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)". Gut.
(2019). "Digestive System Tumours".
(July 2007). "Resected serous cystic neoplasms of the pancreas: a review of 158 patients with recommendations for treatment". Journal of Gastrointestinal Surgery.
"Pathology of Neoplasms of the Pancreas". [[Johns Hopkins University]].
"Pancreatic Surgery". [[Johns Hopkins University]].
"Laproscopic Pancreatic Surgery". [[Johns Hopkins University]].
Wang Y, Miller FH, Chen ZE, Merrick L, Mortele KJ, Hoff FL. (2011). "Diffusion-weighted MR imaging of solid and cystic lesions of the pancreas.". Radiographics.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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