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Oxygenation index

Calculation used to measure oxygen in humans


Calculation used to measure oxygen in humans

The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.

A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2. This would be reflected on the formula as a decrease in the numerator or an increase in the denominator - thus lowering the OI. Typically an OI threshold is set for when a neonate should be placed on ECMO, for example 40.

Equation

: OI = \frac{Fi\ce{O2} \times M_\text{PAW}}{Pa\ce{O2}}

  • Fi\ce{O2}: Fraction of inspired oxygen, in percent;
  • M_\text{PAW}: Mean airway pressure, in mmHg;
  • Pa\ce{O2}: Partial pressure of oxygen in arterial blood, in mmHg.

References

References

  1. Ortiz RM, Cilley RE, Bartlett RH. Extracorporeal membrane oxygenation in pediatric respiratory failure. Pediatr Clin North Am. 1987 Feb;34(1):39-46.
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