Oragene

History

Oragene was invented in the early 2000's by Dr. H. Chaim Birnboim. The composition of Oragene is not related to the widely used method of alkaline extraction of plasmid DNA from bacteria. For the first time, genetic researchers had ready access to large amounts of high quality human DNA through a non-invasive, self-collection sampling procedure. Once collected, the DNA is stable at room temperature for many years.

Features

Oragene is used by academic research institutions, bone marrow donor registries, hospitals, clinical testing laboratories, and direct-to-consumer genetic testing companies who require large amounts of high quality DNA from a large number of donors. The non-invasive collection method offered by Oragene allows collection of DNA from those who might be unwilling to provide a blood sample. In addition, Oragene can be sent via the standard postal system providing the ability for customers to scale their operations on a global basis. Oragene can be used to collect more samples from patients and donors with at-home or in-office point-of-care DNA collection.

Oragene is compatible with a variety of downstream applications including microarrays and next generation sequencing.

Oragene is referenced in over 1100 peer-reviewed scientific journals including the following:

References

References

1. Oragene.Dx DNA Collection Device gets FDA Clearance (http://www.medgadget.com/2011/12/oragene-dx-dna-collection-device-gets-fda-clearance.html)
2. (1979). "A rapid alkaline extraction procedure for screening recombinant plasmid DNA". Nucleic Acids Research.
3. (Sep 2006). "Quality and quantity of saliva DNA obtained from the self-administrated oragene method--a pilot study on the cohort of Swedish men.". Cancer Epidemiol Biomarkers Prev.
4. "Scientific Publications".