Surf Wiki
Save to docs
general/infectious-disease-blood-tests

From Surf Wiki (app.surf) — the open knowledge base

NS1 antigen test

Test for dengue fever

NS1 antigen test
Summary

Test for dengue fever

FieldValue
NameNS1 antigen test
ImageJapanese encephalitis virus NS5 Protein.ogv
CaptionCrystal structure of the dengue virus, which causes dengue fever
ICD10A90
LOINC
OtherCodes

NS1 antigen test (nonstructural protein 1) is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. It has been adopted for use in some 40 nations. The method of detection is through enzyme-linked immunosorbent assay. India has introduced in 2010 the NS1 test costing 1,600 rupees at a private hospital in Mumbai.

Medical use

Dengue testing

The medical use of the NS1 antigen test can be defined to diagnose dengue infections and is effective to 1st day detection. Additionally, NS1 assay is useful for differential diagnostics in regards to flaviviruses.

NS1 is present in the serum of infected persons directly at the onset of clinical symptoms in primary dengue infection and produces a strong humoral response. It is detectable before the appearance of IgM antibodies.

DENV by NS1 antigen is laboratory confirmation of dengue in people also assessing clinical aspects (as well as, taking into account where the individual may have traveled recently). Serological tests such as an immunoglobulin M antibody capture–enzyme-linked immunosorbent assay (MAC-ELISA) and viral RNA detection by reverse transcriptase (RT-PCR) can also be used to diagnose dengue fever.

References

References

  1. "Bio-Rad Launches Test for Early Diagnosis of the Dengue Virus | SelectScience".
  2. Debroy, Sumitra. (September 16, 2010). "Now, get dengue test results in just 48 hours".
  3. "CDC - Laboratory Guidance - Dengue".
  4. (March 2014). "The dengue virus non-structural 1 protein: risks and benefits". Virus Research.
  5. "Dengue - Chapter 3 - 2016 Yellow Book {{!}} Travelers' Health {{!}} CDC".
  6. (July 2016). "A novel indirect ELISA for diagnosis of dengue fever". The Indian Journal of Medical Research.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

infectious-disease-blood-tests dengue-fever
Want to explore this topic further?

Ask Mako anything about NS1 antigen test — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report