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Neonatal hepatitis

Field	Value
name	Neonatal hepatitis
caption	Explanation of neonatal hepatitis
field	Neonatology
width	300px

Neonatal hepatitis refers to many forms of liver dysfunction that affects fetuses and neonates.

Signs and symptoms

The infant with neonatal hepatitis usually has jaundice that appears at one to two months of age, is not gaining weight and growing normally, and has an enlarged liver and spleen. Infants with this condition are usually jaundiced. Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice. In contrast with physiologic neonatal jaundice, infants with neonatal hepatitis present with dark urine. Infants may also present with delayed growth.

Causes

The causes of neonatal hepatitis are many. Viruses that have been identified include cytomegalovirus, rubella virus, hepatitis A and B viruses, herpes simplex viruses, coxsackievirus, echovirus, and paramyxovirus. Metabolic and immune disorders can also cause neonatal hepatitis. Giant cell transformation throughout the parenchyma is common.

Diagnosis

Differential diagnosis

Conditions that can present similarly include galactosaemia, hereditary fructose intolerance, cystic fibrosis, and biliary atresia.

References

(2018). "MacSween's Pathology of the Liver". Elsevier.
(2016). "Pediatric Gastrointestinal and Liver Disease". Elsevier.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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