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N,N'-diacetyllegionaminate synthase


FieldValue
NameN,N'-diacetyllegionaminate synthase
EC_number2.5.1.101

N,N'-diacetyllegionaminate synthase (, neuB (gene), legI (gene)) is an enzyme with systematic name phosphoenolpyruvate:2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose 1-(2-carboxy-2-oxoethyl)transferase. This enzyme catalyses the following chemical reaction

: 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + phosphoenolpyruvate + H2O \rightleftharpoons N,N'-diacetyllegionaminate + phosphate

This enzyme requires a divalent metal such as Mn2+.

References

References

  1. (March 2008). "Biosynthesis of CMP-N,N'-diacetyllegionaminic acid from UDP-N,N'-diacetylbacillosamine in Legionella pneumophila". Biochemistry.
  2. (July 2009). "The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors". Glycobiology.
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