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Myoepithelioma of the head and neck

Field	Value
name	Myoepithelioma of the head and neck
image	Myoepithelioma - very high mag.jpg
caption	Micrograph of a myoepithelioma. H&E stain.
field	Oncology
types	Benign, Malignant (rarely)

Myoepithelioma of the head and neck, also myoepithelioma, is a salivary gland tumour of the head and neck that is usually benign. When malignant, which is exceedingly rare, they are known as malignant myoepithelioma or Myoepithelial carcinoma, and they account for 1% of the salivary tumors with poor prognosis.

As the name suggests, it consists of myoepithelial cells. Classically, they are found in the parotid gland or palate. A similar tumor type may be found in the tongue, referred to as ectomesenchymal chondromyxoid tumor.

Pathology

The myoepithelial cells may be spindled, plasmacytoid, eithelioid or clear. Tubules or epithelium are absent, or present in a small amount (

Diagnosis

Myoepitheliomas are diagnosed from an examination of the tissue by a pathologist.

Image: Myoepithelioma - low mag.jpg | Low mag. Image: Myoepithelioma - high mag.jpg | High mag.

Treatment

Benign myoepithelioma are treated with simple excision. They are less prone to recurrence than pleomorphic adenoma. Malignant myoepitheliomas are excised and have been treated in the past with dacarbazine but are prone to both metastasis and re-occurrence.

References

(Jan 1985). "Myoepithelioma of the head and neck: case report and review.". J Surg Oncol.
(1 January 2014). "Myoepithelial carcinoma of the head and neck: A report of 23 cases and literature review". Cancer Treatment Groups.
(May 1995). "Ectomesenchymal chondromyxoid tumor of the anterior tongue. Nineteen cases of a new clinicopathologic entity". Am J Surg Pathol.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

benign-neoplasms salivary-gland-neoplasia

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