Mucinous nevus

Signs and symptoms

Mucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid. It normally starts to develop in early adulthood or from birth. The main location is the trunk, which includes the back.

Causes

There has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.

Diagnosis

Histologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus. Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.

Treatment

Mucinous nevi are benign and don't need to be treated other than for aesthetic reasons. Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.

References

References

1. Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
2. (2014-09-01). "Mucinous Nevus: Report of a Case and Review of the Literature". JAMA Dermatology.
3. (2010-07-08). "The cellular component of the mucinous nevus consists of CD34-positive fibroblasts". Wiley.
4. (2008). "Familial Mucinous Nevus". Wiley.
5. (2011-09-25). "Acquired and familial mucinous nevus". Wiley.
6. (2018). "Mucinous Nevus". Korean Dermatological Association and The Korean Society for Investigative Dermatology.
7. (2003). "Mucinous naevus with atypical features". Oxford University Press (OUP).
8. (1994). "Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus')". Oxford University Press (OUP).
9. (2009). "Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review". Wiley.