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Matairesinol

Matairesinol is an organic compound. It is classified as a lignan, i.e., a type of phenylpropanoid. It is present in some cereals, such as rye, and together with secoisolariciresinol has attracted much attention for its beneficial nutritional effects.

Metabolism

The plant lignans are precursors of the enterolignans (mammalian lignans). A number of plant lignans are metabolized to the enterolignans (enterodiol and enterolactone) that can potentially reduce the risk of certain cancers and cardiovascular diseases.

Biomedical considerations

Although some studies attribute disease preventative (cardio-protective and hormone associated cancers like breast cancer) benefits of lignans, the results are inconclusive. Matairesinol has been found to act as an agonist of the adiponectin receptor 1 (AdipoR1).

References

References

  1. [http://www.sigmaaldrich.com/US/en/product/sial/40043 Matairesinol] at [[Sigma-Aldrich]]
  2. (2006). "Cereals".
  3. (October 2003). "Studies on the metabolism of the plant lignans secoisolariciresinol and matairesinol". J. Agric. Food Chem..
  4. (March 2005). "Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol". Br. J. Nutr..
  5. [http://lpi.oregonstate.edu/infocenter/phytochemicals/lignans Linus Pauling Institute at Oregon State University]
  6. (2013). "Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay". PLOS ONE.
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adiponectin-receptor-agonists lignans furanones tetrahydrofurans phenols phenol-ethers diols
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