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Major aortopulmonary collateral artery
Arteries that supply blood to the lungs
Arteries that supply blood to the lungs
Major aortopulmonary collateral arteries (or MAPCAs) are arteries that develop to supply blood to the lungs when native pulmonary circulation is underdeveloped. Instead of coming from the pulmonary trunk, supply develops from the aorta and other systemic arteries.{{Cite journal
Pathogenesis and anatomy
Major aortopulmonary collateral arteries (MAPCAs) develop early in embryonic life but regress as the normal pulmonary arteries (vessels that will supply deoxygenated blood to the lungs) develop.{{Cite journal | url-access = subscription
The pulmonary arteries stem from the right side of the heart and usually carry deoxygenated blood from the body to the lungs. The collateral arteries carry blood which has already been oxygenated by the lungs, so they are of little use in helping the body to get oxygen.
Associated conditions
Pulmonary atresia with ventricular septal defect (or Tetralogy of Fallot with pulmonary atresia) will result in the development of systemic collaterals.
Implications of a systemic collateral supply
Major aortopulmonary collateral arteries come from the systemic circulation. Because of this, they will often have higher pressure than that found in the lungs, leading to pulmonary hypertension. These vessels are not programmed to exist beyond early fetal life, and eventually became narrowed.
Treatment
The aim of treatment of the MAPCAs is to group them together and convert their supply to deoxygenated blood from the right side of the heart.
References
This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.
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