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Littoral cell angioma

FieldValue
nameLittoral cell angioma
imageLittoral cell angioma of the spleen - low mag.jpg
captionLow magnification micrograph of a littoral cell angioma. H&E stain.
fieldPathology

Littoral cell angioma, abbreviated LCA, and formally known as littoral cell angioma of the spleen, is a benign tumour of the spleen that arises from the cells that line the red pulp.

Symptoms

LCAs most often are not clinically detectable. On occasion, their first presentation may be with splenic rupture.

Most patients show no symptoms and the tumours are found incidentally.

An indication may be a considerable lowering of blood platelets.

Diagnosis

Littoral cell angiomas show in CT scans. They are diagnosed by pathologists by taking a sample of the tumour via Fine Needle Aspiration or Core Needle Aspiration or from a splenectomy. Histologically, they have anastoming small vascular channels and cystic spaces with papillary projections.

Image: Littoral cell angioma of the spleen - very low mag.jpg | Very low mag. Image: Littoral cell angioma of the spleen - intermed mag.jpg | Intermed. mag. Image: Littoral cell angioma of the spleen - very high mag.jpg | Very high mag.

Treatment

The treatment for a littoral cell angioma is a splenectomy.

References

References

  1. (Jul 2004). "Littoral cell angioma of the spleen.". Ann Acad Med Singap.
  2. (Sep 2001). "Littoral-cell angioma as a cause of splenomegaly.". N Engl J Med.
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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

benign-neoplasms
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