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List of verrucous carcinoma subtypes

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Verrucous carcinoma is a type of squamous cell carcinoma that may be associated with HPV infection (may be subtypes 16 or 18, but types 6 and 11 have also been reported, as have HPV negative variants). Several subtypes of verrucous carcinoma have been described. Treatment of verrucous carcinoma with radiation therapy should be avoided due to the risk of anaplastic transformation.

SubtypeClinical features
Epithelioma cuniculatum (Ackerman tumor, Carcinoma cuniculatum)Arises on the sole of the foot from wart
Giant condyloma of Buschke–Löwenstein tumor (Buschke–Löwenstein tumor, Giant condyloma acuminatum)Genitals affected
Oral florid papillomatosis
Subungual keratoacanthomaOccurs in the setting of immunosuppression or with epidermolytic hyperkeratosis;
May erupt in the setting of systemic lupus erythematosus
Gottron's carcinoid papillomatosis (Papillomatosis cutis carcinoides, Papillomatosis cutis carcinoides of Gottron–Eisenlohr)

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