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List of cutaneous conditions caused by problems with junctional proteins

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Mutations of proteins that hold the cells of the skin together can cause disease. Autoantibodies against proteins that hold the cells of the skin together can also cause disease.

List

Junctional proteinCondition(s)
Desmocollin 1Subcorneal pustular dermatosis type of IgA pemphigus
Desmocollin 2Arrhythmogenic right ventricular dysplasia (ARVD)
Desmoglein 1Striate palmoplantar keratoderma
Pemphigus foliaceous
Bullous impetigo
Staphylococcal scalded skin syndrome
Fogo selvagem
Pemphigus erythematosus
Mucocutaneous pemphigus vulgaris
Desmoglein 2ARVD
Desmoglein 3Mucosal pemphigus vulgaris
Pemphigus vegetans
Desmoglein 4Localized autosomal recessive hypotrichosis
Autosomal recessive monilethrix
DesmoplakinStriate palmoplantar keratoderma
Carvajal syndrome
Skin fragility–wooly hair syndrome
Lethal acantholytic epidermolysis bullosa
ARVD
Paraneoplastic pemphigus
Stevens–Johnson syndrome
PlakoglobinNaxos disease
Striate palmoplantar keratoderma
ARVD
Plakophilin 1Ectodermal dysplasia–skin fragility syndrome
Plakophilin 2ARVD
CorneodesmosinHypertrichosis simplex of the scalp

References

References

  1. M, Orne, Charisse. (2015-01-01). "Pemphigus foliaceus". Dermatology Online Journal.
  2. Beigi, Pooya Khan Mohammad. (2018). "A Clinician's Guide to Pemphigus Vulgaris". Springer, Cham.
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