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List of cutaneous conditions associated with internal malignancy

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This is a list of cutaneous conditions associated with internal malignancy; skin markers of internal cancer. It does not include skin infections associated with cancer or cancers that spread to skin.

Cutaneous conditionInternal malignancy
Erythema gyratum repensLung cancer
Hypertrichosis lanuginosa acquisitaLung cancer
Paraneoplastic pemphigusNon-Hodgkin lymphomaNon-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.
Chronic lymphocytic leukemia
Castleman's disease
Sarcoma
Thymoma
Tripe palmsLung cancer
Tripe palms with acanthosis nigricansStomach cancer
Pityriasis rotundaHepatocellular carcinoma
Migratory thrombophlebitisPancreatic adenocarcinoma
Leser–Trélat signGastrointestinal adenocarcinoma
Acquired ichthyosisHodgkin disease
Pityriasis rotundaHepatocellular carcinoma
Paraneoplastic pigmentationSmall cell bronchial carcinoma
Acrokeratosis paraneoplasticaSquamous cell carcinoma of the upper respiratory or gastrointestinal
Necrolytic migratory erythemaGlucagon secreting
DermatomyositisLung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Scleroderma‐like skin changesCarcinoid syndrome
Paraneoplastic pemphigusB‐cell proliferations and thymoma or thymoma‐like neoplasms; specifically Non Hodgkin's lymphoma (42%)
Dermatitis herpetiformisLymphoma
Porphyria cutanea tarda and variegate porphyriasHepatocellular Carcinoma
Erythroderma and exfoliative dermatitisMycosis fungoides or Sézary syndrome
Pyoderma gangrenosumHematological malignancy
Sweet syndromeHematological malignancy

Footnotes

References

Bibliography

References

  1. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology.
  2. (2021). "Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics". Elsevier.
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