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Lisch epithelial corneal dystrophy

Field	Value
synonyms	Band-shaped and whorled microcystic dystrophy of the corneal epithelium
name	Lisch epithelial corneal dystrophy
image	X-linked recessive.svg
image_size	150px
caption	X-linked recessive is the inheritance pattern of this condition
field	ophthalmology

Lisch epithelial corneal dystrophy (LECD), also known as band-shaped and whorled microcystic dystrophy of the corneal epithelium, is a rare form of corneal dystrophy first described in 1992 by Lisch et al. In one study it was linked to chromosomal region Xp22.3, with as yet unknown candidate genes.

The main features of this disease are bilateral or unilateral gray band-shaped and feathery opacities. They sometimes take on a form of a whirlpool, repeating the known pattern of corneal epithelium renewal. Abrasion of the epithelium in 3 patients brought only temporary relief, with abnormal epithelium regrowth in several months.

Epithelial cells in the zones of opacity were shown to have diffuse cytoplasmic vacuoles with as yet unestablished content.

References

(July 1992). "A new, band-shaped and whorled microcystic dystrophy of the corneal epithelium". [[Am. J. Ophthalmol.]].
(October 2000). "Lisch corneal dystrophy is genetically distinct from Meesmann corneal dystrophy and maps to xp22.3". [[Am. J. Ophthalmol.]].

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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

disorders-of-sclera-and-cornea

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