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Leukocoria

Abnormal white reflection from the eye's retina


Abnormal white reflection from the eye's retina

FieldValue
nameLeukocoria
synonymsLeucocoria, white pupillary reflex
imageRb whiteeye.PNG
captionA child with leukocoria due to retinoblastoma in the left eye
fieldOphthalmology, pediatrics

Leukocoria (also white pupillary reflex) is an abnormal white reflection from the retina of the eye. Leukocoria resembles eyeshine, but leukocoria can also occur in animals that lack eyeshine because their retina lacks a tapetum lucidum.

Leukocoria is a medical sign for a number of conditions, including Coats disease, congenital cataract, corneal scarring, melanoma of the ciliary body, Norrie disease, ocular toxocariasis, persistence of the tunica vasculosa lentis (PFV/PHPV), retinoblastoma, and retrolental fibroplasia.

Because of the potentially life-threatening nature of retinoblastoma, a cancer, that condition is usually considered in the evaluation of leukocoria. In some rare cases (1%) the leukocoria is caused by Coats' disease (leaking retinal vessels).

Diagnosis

On photographs taken using a flash, instead of the familiar red-eye effect, leukocoria can cause a bright white reflection in an affected eye. Leukocoria may appear also in low indirect light, similar to eyeshine.

Leukocoria can be detected by a routine eye exam (see Ophthalmoscopy). For screening purposes, the red reflex test is used. In this test, when a light is shone briefly through the pupil, an orange red reflection is normal. A white reflection is leukocoria.

Image:Fundus photograph-normal retina EDA06.JPG|A normal human fundus Image:Fundus retinoblastoma.jpg|A fundus with retinoblastoma

Society

  • The fictional serial killer known as "The Collector", the main antagonist of the films The Collector (2009) and The Collection (2012), had the condition in both eyes. (confirmed by first movie actor Juan Fernández de Alarcon)

References

References

  1. [http://medical-dictionary.thefreedictionary.com/leukokoria thefreedictionary.com]
  2. (January 2001). "Leucocoria as the presenting sign of a ciliary body melanoma in a child". The British Journal of Ophthalmology.
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