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L-olivosyl-oleandolide 3-O-methyltransferase


FieldValue
NameL-olivosyl-oleandolide 3-O-methyltransferase
EC_number2.1.1.239

L-olivosyl-oleandolide 3-O-methyltransferase (, OleY) is an enzyme with systematic name S-adenosyl-L-methionine:L-olivosyl-oleandolide B 3-O-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + L-olivosyl-oleandolide \rightleftharpoons S-adenosyl-L-homocysteine + L-oleandrosyl-oleandolide

The enzyme is involved in the biosynthesis of the macrolide antibiotic oleandomycin in Streptomyces antibioticus.

References

References

  1. (September 2001). "Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus". Journal of Bacteriology.
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